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Intramolecular Michael Additions in Uridine Derivatives: Isolation of the Labile 5′O-C6 Cyclonucleoside
[Image: see text] Uridine derivatives undergo a diastereospecific intramolecular hetero Michael addition onto uracil C6 to give cyclo-adducts. In contrast to the potent amine and thiol nucleophiles at the 5′ position of ribose, which readily give the N- and S-cyclonucleosides in good yields, the cyc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528289/ https://www.ncbi.nlm.nih.gov/pubmed/33015492 http://dx.doi.org/10.1021/acsomega.0c03348 |