Oral administration of NPC43 counters hyperglycemia and activates insulin receptor in streptozotocin-induced type 1 diabetic mice

INTRODUCTION: Adenosine, 5’-Se-methyl-5’-seleno-,2’,3’-diacetate (NPC43) is a recently identified small, non-peptidyl molecule which restores normal insulin signaling in a mouse model of type 2 diabetes (Lan et al). The present study investigated the ability of NPC43 as an oral and injectable insuli...

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Detalles Bibliográficos
Autores principales: Lan, Zi-Jian, Lei, Zhenmin, Nation, Lucinda, Li, Xian, Yiannikouris, Alexandros, Yerramreddy, Thirupathi Reddy, Kincaid, Hayley, Eastridge, Katie, Xiao, Rijin, Goettl, Ryan, Power, Ronan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Emerging Technologies, Pharmacology and Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528369/
https://www.ncbi.nlm.nih.gov/pubmed/32998869
http://dx.doi.org/10.1136/bmjdrc-2020-001695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528369/
https://www.ncbi.nlm.nih.gov/pubmed/32998869
http://dx.doi.org/10.1136/bmjdrc-2020-001695

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