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Virtual Screening and Bioactivity Evaluation of Novel Androgen Receptor Antagonists From Anti-PCa Traditional Chinese Medicine Prescriptions

Prostate cancer (PCa), a type of malignancy that arises in the prostate gland, is the most commonly diagnosed neoplasm and the second leading cause of cancer-related deaths in men. Acquisition of resistance to conventional therapy is a major problem for PCa patient treatment. Androgen receptor (AR)...

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Detalles Bibliográficos
Autores principales: Han, Wenya, Shi, Yuqi, Su, Jie, Zhao, Zhennan, Wang, Xin, Li, Jiazhong, Liu, Huanxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528374/
https://www.ncbi.nlm.nih.gov/pubmed/33094102
http://dx.doi.org/10.3389/fchem.2020.582861