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Tubulin Tyrosine Ligase Like 4 (TTLL4) overexpression in breast cancer cells is associated with brain metastasis and alters exosome biogenesis

BACKGROUND: The survival rate is poor in breast cancer patients with brain metastases. Thus, new concepts for therapeutic approaches are required. During metastasis, the cytoskeleton of cancer cells is highly dynamic and therefore cytoskeleton-associated proteins are interesting targets for tumour t...

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Detalles Bibliográficos
Autores principales: Arnold, Julia, Schattschneider, Juliana, Blechner, Christine, Krisp, Christoph, Schlüter, Hartmut, Schweizer, Michaela, Nalaskowski, Marcus, Oliveira-Ferrer, Leticia, Windhorst, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528497/
https://www.ncbi.nlm.nih.gov/pubmed/32998758
http://dx.doi.org/10.1186/s13046-020-01712-w