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Exposure–response modelling approaches for determining optimal dosing rules in children
Within paediatric populations, there may be distinct age groups characterised by different exposure–response relationships. Several regulatory guidance documents have suggested general age groupings. However, it is not clear whether these categorisations will be suitable for all new medicines and in...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528535/ https://www.ncbi.nlm.nih.gov/pubmed/32050840 http://dx.doi.org/10.1177/0962280220903751 |