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Exposure–response modelling approaches for determining optimal dosing rules in children

Within paediatric populations, there may be distinct age groups characterised by different exposure–response relationships. Several regulatory guidance documents have suggested general age groupings. However, it is not clear whether these categorisations will be suitable for all new medicines and in...

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Detalles Bibliográficos
Autores principales: Wadsworth, Ian, Hampson, Lisa V, Bornkamp, Björn, Jaki, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528535/
https://www.ncbi.nlm.nih.gov/pubmed/32050840
http://dx.doi.org/10.1177/0962280220903751