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Two-step mechanism for selective incorporation of lncRNA into a chromatin modifier

The MLE DExH helicase and the roX lncRNAs are essential components of the chromatin modifying Dosage Compensation Complex (DCC) in Drosophila. To explore the mechanism of ribonucleoprotein complex assembly, we developed vitRIP, an unbiased, transcriptome-wide in vitro assay that reveals RNA binding...

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Detalles Bibliográficos
Autores principales: Müller, Marisa, Schauer, Tamas, Krause, Silke, Villa, Raffaella, Thomae, Andreas W, Becker, Peter B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528653/
https://www.ncbi.nlm.nih.gov/pubmed/32510132
http://dx.doi.org/10.1093/nar/gkaa492