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MicroRNA 449c Mediates the Generation of Monocytic Myeloid-Derived Suppressor Cells by Targeting STAT6

Myeloid-derived suppressor cells (MDSCs) promote tumour progression by contributing to angiogenesis, immunosuppression, and immunotherapy resistance. Although recent studies have shown that microRNAs (miRNAs) can promote the expansion of MDSCs in the tumour environment, the mechanisms involved in th...

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Detalles Bibliográficos
Autores principales: Han, Xiaoqing, Luan, Tao, Sun, Yingying, Yan, Wenyi, Wang, Dake, Zeng, Xianlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528684/
https://www.ncbi.nlm.nih.gov/pubmed/32863280
http://dx.doi.org/10.14348/molcells.2020.2307