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Yap/Taz promote the scavenging of extracellular nutrients through macropinocytosis

The uptake of macromolecules and cellular debris through macropinocytosis has emerged as an important nutrient acquisition strategy of cancer cells. Genetic alterations commonly found in human cancers (e.g. mutations in KRAS or loss of PTEN) have been shown to increase macropinocytosis. To identify...

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Detalles Bibliográficos
Autores principales: King, Bryan, Araki, Jingwen, Palm, Wilhelm, Thompson, Craig B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528706/
https://www.ncbi.nlm.nih.gov/pubmed/32912902
http://dx.doi.org/10.1101/gad.340661.120