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ASB13 inhibits breast cancer metastasis through promoting SNAI2 degradation and relieving its transcriptional repression of YAP

Transcription factor SNAI2 plays key roles during development and has also been known to promote metastasis by inducing invasive phenotype and tumor-initiating activity of cancer cells. However, the post-translational regulation of SNAI2 is less well studied. We performed a dual-luciferase-based, ge...

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Detalles Bibliográficos
Autores principales: Fan, Huijuan, Wang, Xuxiang, Li, Wenyang, Shen, Minhong, Wei, Yong, Zheng, Hanqiu, Kang, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528707/
https://www.ncbi.nlm.nih.gov/pubmed/32943576
http://dx.doi.org/10.1101/gad.339796.120