Cargando…
Interleukin 6 reduces allopregnanolone synthesis in the brain and contributes to age-related cognitive decline in mice
Cognitive decline with age is a harmful process that can reduce quality of life. Multiple factors have been established to contribute to cognitive decline, but the overall etiology remains unknown. Here, we hypothesized that cognitive dysfunction is mediated, in part, by increased levels of inflamma...
Autores principales: | Parks, Eileen E., Logan, Sreemathi, Yeganeh, Alexander, Farley, Julie A., Owen, Daniel B., Sonntag, William E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529050/ https://www.ncbi.nlm.nih.gov/pubmed/32669383 http://dx.doi.org/10.1194/jlr.RA119000479 |
Ejemplares similares
-
Progressive cognitive impairment after recovery from neuroinvasive and non-neuroinvasive Listeria monocytogenes infection
por: Cassidy, Benjamin R., et al.
Publicado: (2023) -
Allopregnanolone: An overview on its synthesis and effects
por: Diviccaro, Silvia, et al.
Publicado: (2021) -
Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes
por: Logan, Sreemathi, et al.
Publicado: (2018) -
Disparate Central and Peripheral Effects of Circulating IGF-1 Deficiency on Tissue Mitochondrial Function
por: Pharaoh, Gavin, et al.
Publicado: (2019) -
Allopregnanolone in Postpartum Depression
por: Pinna, Graziano, et al.
Publicado: (2022)