Genome-wide CRISPR knockout screen identifies ZNF304 as a silencer of HIV transcription that promotes viral latency

Despite the widespread use of anti-retroviral therapy, human immunodeficiency virus (HIV) still persists in an infected cell reservoir that harbors transcriptionally silent yet replication-competent proviruses. While significant progress has been made in understanding how the HIV reservoir is establ...

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Detalles Bibliográficos
Autores principales: Krasnopolsky, Simona, Kuzmina, Alona, Taube, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529202/
https://www.ncbi.nlm.nih.gov/pubmed/32956422
http://dx.doi.org/10.1371/journal.ppat.1008834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529202/
https://www.ncbi.nlm.nih.gov/pubmed/32956422
http://dx.doi.org/10.1371/journal.ppat.1008834

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