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KRAS mutation status concordance between the primary tumor and the corresponding metastasis in patients with rectal cancer

INTRODUCTION: Oncogenic mutation within the KRAS gene represents a negative predictor for treatment response to anti-epidermal growth factor receptor (EGFR) in patients with colorectal cancer. Recently, we have shown no relevant heterogeneity for KRAS mutation status within and between pre- and post...

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Detalles Bibliográficos
Autores principales: Jo, Peter, Bernhardt, Markus, Nietert, Manuel, König, Alexander, Azizian, Azadeh, Schirmer, Markus A., Grade, Marian, Kitz, Julia, Reuter-Jessen, Kirsten, Ghadimi, Michael, Ströbel, Philipp, Schildhaus, Hans-Ulrich, Gaedcke, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529221/
https://www.ncbi.nlm.nih.gov/pubmed/33002027
http://dx.doi.org/10.1371/journal.pone.0239806