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KRAS mutation status concordance between the primary tumor and the corresponding metastasis in patients with rectal cancer
INTRODUCTION: Oncogenic mutation within the KRAS gene represents a negative predictor for treatment response to anti-epidermal growth factor receptor (EGFR) in patients with colorectal cancer. Recently, we have shown no relevant heterogeneity for KRAS mutation status within and between pre- and post...
Autores principales: | Jo, Peter, Bernhardt, Markus, Nietert, Manuel, König, Alexander, Azizian, Azadeh, Schirmer, Markus A., Grade, Marian, Kitz, Julia, Reuter-Jessen, Kirsten, Ghadimi, Michael, Ströbel, Philipp, Schildhaus, Hans-Ulrich, Gaedcke, Jochen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529221/ https://www.ncbi.nlm.nih.gov/pubmed/33002027 http://dx.doi.org/10.1371/journal.pone.0239806 |
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