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Is C-type natriuretic peptide regulated by a feedback loop? A study on systemic and local autoregulatory effect

C-type natriuretic peptide (CNP) is a pivotal enhancer of endochondral bone growth and is expected to be a therapeutic reagent for impaired skeletal growth. Although we showed that CNP stimulates bone growth as a local regulator in the growth plate via the autocrine/paracrine system, CNP is abundant...

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Detalles Bibliográficos
Autores principales: Ueda, Yohei, Hirota, Keisho, Yamauchi, Ichiro, Hakata, Takuro, Yamashita, Takafumi, Fujii, Toshihito, Yasoda, Akihiro, Inagaki, Nobuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529242/
https://www.ncbi.nlm.nih.gov/pubmed/33002060
http://dx.doi.org/10.1371/journal.pone.0240023