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Is C-type natriuretic peptide regulated by a feedback loop? A study on systemic and local autoregulatory effect
C-type natriuretic peptide (CNP) is a pivotal enhancer of endochondral bone growth and is expected to be a therapeutic reagent for impaired skeletal growth. Although we showed that CNP stimulates bone growth as a local regulator in the growth plate via the autocrine/paracrine system, CNP is abundant...
Autores principales: | Ueda, Yohei, Hirota, Keisho, Yamauchi, Ichiro, Hakata, Takuro, Yamashita, Takafumi, Fujii, Toshihito, Yasoda, Akihiro, Inagaki, Nobuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529242/ https://www.ncbi.nlm.nih.gov/pubmed/33002060 http://dx.doi.org/10.1371/journal.pone.0240023 |
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