Silencing miR-202-3p increases MMP-1 and promotes a brain invasive phenotype in metastatic breast cancer cells

BACKGROUND: Brain metastasis (BM) is a major cause of morbidity and mortality in breast cancer (BC) and its molecular mechanism remains poorly understood. Transmigration of metastatic cells through the brain endothelium is an essential step in BM. Metalloproteinase-1 (MMP-1) overexpression plays a k...

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Detalles Bibliográficos
Autores principales: Harati, Rania, Hafezi, Shirin, Mabondzo, Aloïse, Tlili, Abdelaziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529272/
https://www.ncbi.nlm.nih.gov/pubmed/33002044
http://dx.doi.org/10.1371/journal.pone.0239292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529272/
https://www.ncbi.nlm.nih.gov/pubmed/33002044
http://dx.doi.org/10.1371/journal.pone.0239292

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