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Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin

Epidemiological studies reveal significant associations between periodontitis and oral cancer. However, knowledge about the contribution of periodontal pathogens to oral cancer and potential regulatory mechanisms involved is limited. Previously, we showed that nisin, a bacteriocin and commonly used...

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Detalles Bibliográficos
Autores principales: Kamarajan, Pachiyappan, Ateia, Islam, Shin, Jae M., Fenno, J. Christopher, Le, Charles, Zhan, Ling, Chang, Ana, Darveau, Richard, Kapila, Yvonne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529280/
https://www.ncbi.nlm.nih.gov/pubmed/33002094
http://dx.doi.org/10.1371/journal.ppat.1008881