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Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin
Epidemiological studies reveal significant associations between periodontitis and oral cancer. However, knowledge about the contribution of periodontal pathogens to oral cancer and potential regulatory mechanisms involved is limited. Previously, we showed that nisin, a bacteriocin and commonly used...
Autores principales: | Kamarajan, Pachiyappan, Ateia, Islam, Shin, Jae M., Fenno, J. Christopher, Le, Charles, Zhan, Ling, Chang, Ana, Darveau, Richard, Kapila, Yvonne L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529280/ https://www.ncbi.nlm.nih.gov/pubmed/33002094 http://dx.doi.org/10.1371/journal.ppat.1008881 |
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