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Reorganization of the nuclear architecture in the Drosophila melanogaster Lamin B mutant lacking the CaaX box

Lamins interact with the nuclear membrane and chromatin but the precise players and mechanisms of these interactions are unknown. Here, we tested whether the removal of the CaaX motif from Lamin B disrupts its attachment to the nuclear membrane and affects chromatin distribution. We used Drosophila...

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Detalles Bibliográficos
Autores principales: Bondarenko, Semen M., Sharakhov, Igor V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529411/
https://www.ncbi.nlm.nih.gov/pubmed/32960740
http://dx.doi.org/10.1080/19491034.2020.1819704