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A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors

Understanding the cellular constituents of the prostate is essential for identifying the cell of origin for prostate adenocarcinoma. Here, we describe a comprehensive single-cell atlas of the adult mouse prostate epithelium, which displays extensive heterogeneity. We observe distal lobe-specific lum...

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書目詳細資料
Autores principales: Crowley, Laura, Cambuli, Francesco, Aparicio, Luis, Shibata, Maho, Robinson, Brian D, Xuan, Shouhong, Li, Weiping, Hibshoosh, Hanina, Loda, Massimo, Rabadan, Raul, Shen, Michael M
格式: Online Artículo Texto
語言:English
出版: eLife Sciences Publications, Ltd 2020
主題:
在線閱讀:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529463/
https://www.ncbi.nlm.nih.gov/pubmed/32915138
http://dx.doi.org/10.7554/eLife.59465