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A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors

Understanding the cellular constituents of the prostate is essential for identifying the cell of origin for prostate adenocarcinoma. Here, we describe a comprehensive single-cell atlas of the adult mouse prostate epithelium, which displays extensive heterogeneity. We observe distal lobe-specific lum...

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Detalles Bibliográficos
Autores principales: Crowley, Laura, Cambuli, Francesco, Aparicio, Luis, Shibata, Maho, Robinson, Brian D, Xuan, Shouhong, Li, Weiping, Hibshoosh, Hanina, Loda, Massimo, Rabadan, Raul, Shen, Michael M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529463/
https://www.ncbi.nlm.nih.gov/pubmed/32915138
http://dx.doi.org/10.7554/eLife.59465