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Serum- and glucocorticoid- inducible kinase 2, SGK2, is a novel autophagy regulator and modulates platinum drugs response in cancer cells

For many tumor types chemotherapy still represents the therapy of choice and many standard treatments are based on the use of platinum (PT) drugs. However, de novo or acquired resistance to platinum is frequent and leads to disease progression. In Epithelial Ovarian Cancer (EOC) patients, PT-resista...

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Detalles Bibliográficos
Autores principales: Ranzuglia, Valentina, Lorenzon, Ilaria, Pellarin, Ilenia, Sonego, Maura, Dall’Acqua, Alessandra, D’Andrea, Sara, Lovisa, Sara, Segatto, Ilenia, Coan, Michela, Polesel, Jerry, Serraino, Diego, Sabatelli, Patrizia, Spessotto, Paola, Belletti, Barbara, Baldassarre, Gustavo, Schiappacassi, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529585/
https://www.ncbi.nlm.nih.gov/pubmed/32848212
http://dx.doi.org/10.1038/s41388-020-01433-6