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Serum- and glucocorticoid- inducible kinase 2, SGK2, is a novel autophagy regulator and modulates platinum drugs response in cancer cells
For many tumor types chemotherapy still represents the therapy of choice and many standard treatments are based on the use of platinum (PT) drugs. However, de novo or acquired resistance to platinum is frequent and leads to disease progression. In Epithelial Ovarian Cancer (EOC) patients, PT-resista...
Autores principales: | Ranzuglia, Valentina, Lorenzon, Ilaria, Pellarin, Ilenia, Sonego, Maura, Dall’Acqua, Alessandra, D’Andrea, Sara, Lovisa, Sara, Segatto, Ilenia, Coan, Michela, Polesel, Jerry, Serraino, Diego, Sabatelli, Patrizia, Spessotto, Paola, Belletti, Barbara, Baldassarre, Gustavo, Schiappacassi, Monica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529585/ https://www.ncbi.nlm.nih.gov/pubmed/32848212 http://dx.doi.org/10.1038/s41388-020-01433-6 |
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