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Novel acyl carbamates and acyl / diacyl ureas show in vitro efficacy against Toxoplasma gondii and Cryptosporidium parvum

Toxoplasma gondii and Cryptosporidium parvum are protozoan parasites that are highly prevalent and opportunistically infect humans worldwide, but for which completely effective and safe medications are lacking. Herein, we synthesized a series of novel small molecules bearing the diacyl urea scaffold...

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Detalles Bibliográficos
Autores principales: Li, Kun, Grooms, Gregory M., Khan, Shahbaz M., Hernandez, Anolan Garcia, Witola, William H., Stec, Jozef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529613/
https://www.ncbi.nlm.nih.gov/pubmed/33011650
http://dx.doi.org/10.1016/j.ijpddr.2020.08.006