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Intraductal Pancreatic Cancer is Less Responsive Than Cancer in the Stroma to Neoadjuvant Chemotherapy

Neoadjuvant chemotherapy (NAC) is often the treatment of choice for borderline resectable and locally advanced invasive pancreatic ductal adenocarcinoma (PDAC); however, most cancers only partially respond to therapy. We hypothesized that the location of residual neoplastic cells in resected specime...

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Detalles Bibliográficos
Autores principales: Fujikura, Kohei, Hutchings, Danielle, Braxton, Alicia M., Zhu, Qingfeng, Laheru, Daniel A., Hruban, Ralph H., Thompson, Elizabeth D., Wood, Laura D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529702/
https://www.ncbi.nlm.nih.gov/pubmed/32457408
http://dx.doi.org/10.1038/s41379-020-0572-6