The human milk oligosaccharides 2’-Fucosyllactose and 6’-Sialyllactose protect against the development of necrotizing enterocolitis by inhibiting Toll-Like Receptor 4 signaling.

OBJECTIVE: Necrotizing enterocolitis (NEC) develops through exaggerated toll-like receptor 4 (TLR4) signaling in the intestinal epithelium. Breast milk is rich in non-digestible oligosaccharides and prevents NEC through unclear mechanisms. We now hypothesize that the human milk oligosaccharides 2’-F...

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Detalles Bibliográficos
Autores principales: Sodhi, Chhinder P., Wipf, Peter, Yamaguchi, Yukihiro, Fulton, William B., Kovler, Mark, Niño, Diego F., Zhou, Qinjie, Banfield, Emilyn, Werts, Adam D., Ladd, Mitchell R., Buck, Rachael H., Goehring, Karen C., Prindle, Thomas, Wang, Sanxia, Jia, Hongpeng, Lu, Peng, Hackam, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529714/
https://www.ncbi.nlm.nih.gov/pubmed/32221473
http://dx.doi.org/10.1038/s41390-020-0852-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529714/
https://www.ncbi.nlm.nih.gov/pubmed/32221473
http://dx.doi.org/10.1038/s41390-020-0852-3

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