BAFF-driven NLRP3 inflammasome activation in B cells

BAFF supports B-cell survival and homeostasis by activating the NF-κB pathway. While NF-κB is also involved in the priming signal of NLRP3 inflammasome, the role of BAFF in NLRP3 inflammasome regulation is unknown. Here we report BAFF engagement to BAFF receptor elicited both priming and activating...

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Detalles Bibliográficos
Autores principales: Lim, Ken-Hong, Chen, Lih-Chyang, Hsu, Kate, Chang, Chia-Ching, Chang, Chia-Yu, Kao, Chen-Wei, Chang, Yi-Fang, Chang, Ming-Chih, Chen, Caleb Gonshen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529748/
https://www.ncbi.nlm.nih.gov/pubmed/33004801
http://dx.doi.org/10.1038/s41419-020-03035-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529748/
https://www.ncbi.nlm.nih.gov/pubmed/33004801
http://dx.doi.org/10.1038/s41419-020-03035-2

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