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BAFF-driven NLRP3 inflammasome activation in B cells
BAFF supports B-cell survival and homeostasis by activating the NF-κB pathway. While NF-κB is also involved in the priming signal of NLRP3 inflammasome, the role of BAFF in NLRP3 inflammasome regulation is unknown. Here we report BAFF engagement to BAFF receptor elicited both priming and activating...
Autores principales: | Lim, Ken-Hong, Chen, Lih-Chyang, Hsu, Kate, Chang, Chia-Ching, Chang, Chia-Yu, Kao, Chen-Wei, Chang, Yi-Fang, Chang, Ming-Chih, Chen, Caleb Gonshen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529748/ https://www.ncbi.nlm.nih.gov/pubmed/33004801 http://dx.doi.org/10.1038/s41419-020-03035-2 |
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