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Cytotoxic activity of bromodomain inhibitor NVS-CECR2-1 on human cancer cells

Bromodomain (BRD), a protein module that recognizes acetylated lysine residues on histones and other proteins, has recently emerged as a promising therapeutic target for human diseases such as cancer. While most of the studies have been focused on inhibitors against BRDs of the bromo- and extra-term...

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Detalles Bibliográficos
Autores principales: Park, Seul Gi, Lee, Daye, Seo, Hye-Ran, Lee, Shin-Ai, Kwon, Jongbum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529788/
https://www.ncbi.nlm.nih.gov/pubmed/33004947
http://dx.doi.org/10.1038/s41598-020-73500-7