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Metal ions shape α-synuclein

α-Synuclein is an intrinsically disordered protein that can self-aggregate and plays a major role in Parkinson’s disease (PD). Elevated levels of certain metal ions are found in protein aggregates in neurons of people suffering from PD, and environmental exposure has also been linked with neurodegen...

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Detalles Bibliográficos
Autores principales: Moons, Rani, Konijnenberg, Albert, Mensch, Carl, Van Elzen, Roos, Johannessen, Christian, Maudsley, Stuart, Lambeir, Anne-Marie, Sobott, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529799/
https://www.ncbi.nlm.nih.gov/pubmed/33004902
http://dx.doi.org/10.1038/s41598-020-73207-9