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The allosteric activation mechanism of a phospholipase A(2)-like toxin from Bothrops jararacussu venom: a dynamic description

The activation process of phospholipase A(2)-like (PLA(2)-like) toxins is a key step in their molecular mechanism, which involves oligomeric changes leading to the exposure of specific sites. Few studies have focused on the characterization of allosteric activators and the features that distinguish...

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Detalles Bibliográficos
Autores principales: Gomes, Antoniel A. S., Cardoso, Fabio F., Souza, Maximilia F., Oliveira, Cristiano L. P., Perahia, David, Magro, Angelo J., Fontes, Marcos R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529814/
https://www.ncbi.nlm.nih.gov/pubmed/33004851
http://dx.doi.org/10.1038/s41598-020-73134-9