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Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers

Non-invasive, molecularly-specific, focal modulation of brain circuits with low off-target effects can lead to breakthroughs in treatments of brain disorders. We systemically inject engineered ultrasound-controllable drug carriers and subsequently apply a novel two-component Aggregation and Uncaging...

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Detalles Bibliográficos
Autores principales: Ozdas, Mehmet S., Shah, Aagam S., Johnson, Paul M., Patel, Nisheet, Marks, Markus, Yasar, Tansel Baran, Stalder, Urs, Bigler, Laurent, von der Behrens, Wolfger, Sirsi, Shashank R., Yanik, Mehmet Fatih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529901/
https://www.ncbi.nlm.nih.gov/pubmed/33004789
http://dx.doi.org/10.1038/s41467-020-18059-7