Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogram the host immune response during persistent infection

Staphylococcus aureus (S. aureus) is a leading cause of biofilm-associated prosthetic joint infection (PJI), resulting in significant disability and prolonged treatment. It is known that host leukocyte IL-10 production is required for S. aureus biofilm persistence in PJI. A S. aureus bursa aurealis...

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Detalles Bibliográficos
Autores principales: Heim, Cortney E., Bosch, Megan E., Yamada, Kelsey J., Aldrich, Amy L., Chaudhari, Sujata S., Klinkebiel, David, Gries, Casey M., Alqarzaee, Abdulelah A., Li, Yixuan, Thomas, Vinai C., Seto, Edward, Karpf, Adam R., Kielian, Tammy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529909/
https://www.ncbi.nlm.nih.gov/pubmed/32661313
http://dx.doi.org/10.1038/s41564-020-0756-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529909/
https://www.ncbi.nlm.nih.gov/pubmed/32661313
http://dx.doi.org/10.1038/s41564-020-0756-3

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