Cargando…

Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogram the host immune response during persistent infection

Staphylococcus aureus (S. aureus) is a leading cause of biofilm-associated prosthetic joint infection (PJI), resulting in significant disability and prolonged treatment. It is known that host leukocyte IL-10 production is required for S. aureus biofilm persistence in PJI. A S. aureus bursa aurealis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Heim, Cortney E., Bosch, Megan E., Yamada, Kelsey J., Aldrich, Amy L., Chaudhari, Sujata S., Klinkebiel, David, Gries, Casey M., Alqarzaee, Abdulelah A., Li, Yixuan, Thomas, Vinai C., Seto, Edward, Karpf, Adam R., Kielian, Tammy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529909/ https://www.ncbi.nlm.nih.gov/pubmed/32661313 http://dx.doi.org/10.1038/s41564-020-0756-3

Ejemplares similares

Staphylococcus aureus ATP Synthase Promotes Biofilm Persistence by Influencing Innate Immunity
por: Bosch, Megan E., et al.
Publicado: (2020)

A critical role for staphylococcal nitric oxide synthase in controlling flavohemoglobin toxicity
por: Singh, Ryan M., et al.
Publicado: (2023)

Monocyte metabolic reprogramming promotes pro-inflammatory activity and Staphylococcus aureus biofilm clearance
por: Yamada, Kelsey J., et al.
Publicado: (2020)

TLR2 and caspase-1 signaling are critical for bacterial containment but not clearance during craniotomy-associated biofilm infection
por: Aldrich, Amy L., et al.
Publicado: (2020)

Hiding in Plain Sight: Interplay between Staphylococcal Biofilms and Host Immunity
por: Scherr, Tyler D., et al.
Publicado: (2014)

Transformation of Human Cathelicidin LL-37 into Selective, Stable, and Potent Antimicrobial Compounds
por: Wang, Guangshun, et al.
Publicado: (2014)

Nitrite Derived from Endogenous Bacterial Nitric Oxide Synthase Activity Promotes Aerobic Respiration
por: Chaudhari, Sujata S., et al.
Publicado: (2017)

Urease is an essential component of the acid response network of Staphylococcus aureus and is required for a persistent murine kidney infection
por: Zhou, Chunyi, et al.
Publicado: (2019)

Exploring epigenetic reprogramming during central nervous system infection
por: Van Roy, Zachary, et al.
Publicado: (2022)

Potassium Uptake Modulates Staphylococcus aureus Metabolism
por: Gries, Casey M., et al.
Publicado: (2016)

Hemichannels in neurodegenerative diseases: is there a link to pathology?
por: Bosch, Megan, et al.
Publicado: (2014)

The ClpXP protease is dispensable for degradation of unfolded proteins in Staphylococcus aureus
por: Stahlhut, Steen G., et al.
Publicado: (2017)

IL-10 production by granulocytes promotes Staphylococcus aureus craniotomy infection
por: Kak, Gunjan, et al.
Publicado: (2023)

Neuroinflammatory paradigms in lysosomal storage diseases
por: Bosch, Megan E., et al.
Publicado: (2015)

An integrated computational and experimental study to investigate Staphylococcus aureus metabolism
por: Mazharul Islam, Mohammad, et al.
Publicado: (2020)

Deciphering mechanisms of staphylococcal biofilm evasion of host immunity
por: Hanke, Mark L., et al.
Publicado: (2012)

HDAC8 affects MGMT levels in glioblastoma cell lines via interaction with the proteasome receptor ADRM1
por: Santos-Barriopedro, Irene, et al.
Publicado: (2019)

Immunopathogenesis of brain abscess
por: Kielian, Tammy
Publicado: (2004)

Efficacy of phosphodiesterase‐4 inhibitors in juvenile Batten disease (CLN3)
por: Aldrich, Amy, et al.
Publicado: (2016)

MyD88-Dependent Signaling Influences Fibrosis and Alternative Macrophage Activation during Staphylococcus aureus Biofilm Infection
por: Hanke, Mark L., et al.
Publicado: (2012)

Lactate-Lactylation Hands between Metabolic Reprogramming and Immunosuppression
por: Chen, Lihua, et al.
Publicado: (2022)

Emerging roles of histone modifications and HDACs in RNA splicing
por: Rahhal, Raneen, et al.
Publicado: (2019)

Neutrophils are mediators of metastatic prostate cancer progression in bone
por: Costanzo-Garvey, Diane L., et al.
Publicado: (2020)

Effects of low dose GM-CSF on microglial inflammatory profiles to diverse pathogen-associated molecular patterns (PAMPs)
por: Esen, Nilufer, et al.
Publicado: (2007)

MyD88 is pivotal for immune recognition of Citrobacter koseri and astrocyte activation during CNS infection(†)
por: Liu, Shuliang, et al.
Publicado: (2011)

Differential effects of interleukin-17 receptor signaling on innate and adaptive immunity during central nervous system bacterial infection
por: Vidlak, Debbie, et al.
Publicado: (2012)

Immunopathogenesis of Craniotomy Infection and Niche-Specific Immune Responses to Biofilm
por: de Morais, Sharon DB, et al.
Publicado: (2021)

Low levels of AMPK promote epithelial‐mesenchymal transition in lung cancer primarily through HDAC4‐ and HDAC5‐mediated metabolic reprogramming
por: Feng, Shoujie, et al.
Publicado: (2020)

Orthopaedic Surgery Elicits a Systemic Anti-Inflammatory Signature
por: Heim, Cortney E., et al.
Publicado: (2020)

Identification of Potential Cerebrospinal Fluid Biomarkers To Discriminate between Infection and Sterile Inflammation in a Rat Model of Staphylococcus epidermidis Catheter Infection
por: Skar, Gwenn L., et al.
Publicado: (2019)

Crosstalk Between Staphylococcus aureus and Innate Immunity: Focus on Immunometabolism
por: Horn, Christopher M., et al.
Publicado: (2021)

Lactate-related metabolic reprogramming and immune regulation in colorectal cancer
por: Sun, Qianhui, et al.
Publicado: (2023)

Checkpoint regulator B7x is epigenetically regulated by HDAC3 and mediates resistance to HDAC inhibitors by reprogramming the tumor immune environment in colorectal cancer
por: Li, Yuxin, et al.
Publicado: (2020)

Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming
por: Oger, Frédérik, et al.
Publicado: (2023)

Lactate Induces Pro-tumor Reprogramming in Intratumoral Plasmacytoid Dendritic Cells
por: Raychaudhuri, Deblina, et al.
Publicado: (2019)

Global DNA Hypomethylation in Epithelial Ovarian Cancer: Passive Demethylation and Association with Genomic Instability
por: Zhang, Wa, et al.
Publicado: (2020)

Programming and Regulation of Metabolic Homeostasis by HDAC11
por: Sun, Lei, et al.
Publicado: (2018)

PRAME expression and promoter hypomethylation in epithelial ovarian cancer
por: Zhang, Wa, et al.
Publicado: (2016)

Therapeutic potential of HDAC6 in amyotrophic lateral sclerosis
por: Guo, Wenting, et al.
Publicado: (2017)

Trapoxin A Analogue as a Selective Nanomolar Inhibitor of HDAC11
por: Ho, Thanh Tu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_p49d9c9rhulckoeo7n3e2mlrfk