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Neanderthal introgression reintroduced functional ancestral alleles lost in Eurasian populations

Neanderthal ancestry remains across modern Eurasian genomes, and introgressed sequences influence diverse phenotypes. Here we demonstrate that introgressed sequences reintroduced thousands of ancestral alleles that were lost in Eurasian populations prior to introgression. Our simulations and variant...

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Detalles Bibliográficos
Autores principales: Rinker, David C., Simonti, Corinne N., McArthur, Evonne, Shaw, Douglas, Hodges, Emily, Capra, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529911/
https://www.ncbi.nlm.nih.gov/pubmed/32719451
http://dx.doi.org/10.1038/s41559-020-1261-z