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Biosynthesis of medicinal tropane alkaloids in yeast
Tropane alkaloids (TAs) from nightshade plants are neurotransmitter inhibitors used for treating neuromuscular disorders and are classified as essential medicines by the World Health Organization(1,2). Global supply challenges have resulted in frequent drug shortages(3,4). Further supply-chain vulne...
Autores principales: | Srinivasan, Prashanth, Smolke, Christina D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529995/ https://www.ncbi.nlm.nih.gov/pubmed/32879484 http://dx.doi.org/10.1038/s41586-020-2650-9 |
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