Human iPSC-Based Models for the Development of Therapeutics Targeting Neurodegenerative Lysosomal Storage Diseases

Lysosomal storage diseases (LSDs) are a group of rare genetic conditions. The absence or deficiency of lysosomal proteins leads to excessive storage of undigested materials and drives secondary pathological mechanisms including autophagy, calcium homeostasis, ER stress, and mitochondrial abnormaliti...

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Detalles Bibliográficos
Autores principales: Luciani, Marco, Gritti, Angela, Meneghini, Vasco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530250/
https://www.ncbi.nlm.nih.gov/pubmed/33062642
http://dx.doi.org/10.3389/fmolb.2020.00224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530250/
https://www.ncbi.nlm.nih.gov/pubmed/33062642
http://dx.doi.org/10.3389/fmolb.2020.00224

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