Arming HSV-Based Oncolytic Viruses with the Ability to Redirect the Host’s Innate Antiviral Immunity to Attack Tumor Cells

One of the major hurdles for cancer immunotherapy is the host’s innate antiviral defense mechanisms. They include innate immune cells, such as natural killer (NK) cells and macrophages, which can be recruited within hours to the site of injection to clear the introduced oncolytic viruses. Here, we r...

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Detalles Bibliográficos
Autores principales: Fu, Xinping, Tao, Lihua, Wu, Wanfu, Zhang, Xiaoliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530262/
https://www.ncbi.nlm.nih.gov/pubmed/33024817
http://dx.doi.org/10.1016/j.omto.2020.09.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530262/
https://www.ncbi.nlm.nih.gov/pubmed/33024817
http://dx.doi.org/10.1016/j.omto.2020.09.002

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