Propionic Acid Targets the TLR4/NF-κB Signaling Pathway and Inhibits LPS-Induced Intestinal Barrier Dysfunction: In Vitro and In Vivo Studies

Intestinal barrier dysfunction contributes to the development of intestinal diseases. Propionic acid (PA), a metabolite generated by anaerobic fermentation of dietary fiber in the intestinal cavity, has been proved to exert anti-inflammatory effects in a variety of diseases. However, the exact role...

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Detalles Bibliográficos
Autores principales: Yang, Randong, Hu, Xiaoxiao, Xie, Xianzheng, Chen, Haiqiong, Fang, Huangyi, Zhu, Libing, Li, Zhongrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530265/
https://www.ncbi.nlm.nih.gov/pubmed/33041816
http://dx.doi.org/10.3389/fphar.2020.573475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530265/
https://www.ncbi.nlm.nih.gov/pubmed/33041816
http://dx.doi.org/10.3389/fphar.2020.573475

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