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Propionic Acid Targets the TLR4/NF-κB Signaling Pathway and Inhibits LPS-Induced Intestinal Barrier Dysfunction: In Vitro and In Vivo Studies
Intestinal barrier dysfunction contributes to the development of intestinal diseases. Propionic acid (PA), a metabolite generated by anaerobic fermentation of dietary fiber in the intestinal cavity, has been proved to exert anti-inflammatory effects in a variety of diseases. However, the exact role...
Autores principales: | Yang, Randong, Hu, Xiaoxiao, Xie, Xianzheng, Chen, Haiqiong, Fang, Huangyi, Zhu, Libing, Li, Zhongrong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530265/ https://www.ncbi.nlm.nih.gov/pubmed/33041816 http://dx.doi.org/10.3389/fphar.2020.573475 |
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