Circadian Rhythm Protein Bmal1 Modulates Cartilage Gene Expression in Temporomandibular Joint Osteoarthritis via the MAPK/ERK Pathway

The purpose of this study was to elucidate the role of the circadian gene Bmal1 in human cartilage and its crosstalk with the MAPK/ERK signaling pathway in temporomandibular joint osteoarthritis (TMJ-OA). We verified the periodical variation of the circadian gene Bmal1 and then established a modifie...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Guokun, Zhao, Haoming, Ma, Shixing, Chen, Lei, Wu, Gaoyi, Zhu, Yong, Zhu, Jie, Ma, Chuan, Zhao, Huaqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530270/
https://www.ncbi.nlm.nih.gov/pubmed/33041790
http://dx.doi.org/10.3389/fphar.2020.527744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530270/
https://www.ncbi.nlm.nih.gov/pubmed/33041790
http://dx.doi.org/10.3389/fphar.2020.527744

Ejemplares similares