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Circadian Rhythm Protein Bmal1 Modulates Cartilage Gene Expression in Temporomandibular Joint Osteoarthritis via the MAPK/ERK Pathway

The purpose of this study was to elucidate the role of the circadian gene Bmal1 in human cartilage and its crosstalk with the MAPK/ERK signaling pathway in temporomandibular joint osteoarthritis (TMJ-OA). We verified the periodical variation of the circadian gene Bmal1 and then established a modifie...

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Detalles Bibliográficos
Autores principales:	Chen, Guokun, Zhao, Haoming, Ma, Shixing, Chen, Lei, Wu, Gaoyi, Zhu, Yong, Zhu, Jie, Ma, Chuan, Zhao, Huaqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530270/ https://www.ncbi.nlm.nih.gov/pubmed/33041790 http://dx.doi.org/10.3389/fphar.2020.527744

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