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GLT25D2 Is Critical for Inflammatory Immune Response to Promote Acetaminophen-Induced Hepatotoxicity by Autophagy Pathway

Acetaminophen (APAP) overdose induces hepatocyte necrosis and causes liver hepatotoxicity. Currently, the role of galactosyltransferase in APAP-induced liver injury is still unclear. This study assessed the contribution of the GLT25D2 gene, a kind of collagen galactosyltransferase, to the developmen...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaohui, Guo, Lele, Zhang, Xiangying, Xu, Ling, Tian, Yuan, Fan, Zihao, Wei, Hongshan, Zhang, Jing, Ren, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530273/
https://www.ncbi.nlm.nih.gov/pubmed/33071774
http://dx.doi.org/10.3389/fphar.2020.01187