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The correlation of IRE1α oxidation with Nox4 activation in aging-associated vascular dysfunction

Oxidative stress attributable to the activation of a Nox4-containing NADPH oxidase is involved in aging-associated vascular dysfunction. However, the Nox4-induced signaling mechanism for the vascular alteration in aging remains unclear. In an aged aorta, the expression of Nox4 mRNA and protein by No...

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Detalles Bibliográficos
Autores principales: Lee, Hwa-Young, Kim, Hyun-Kyoung, Hoang, The-Hiep, Yang, Siyoung, Kim, Hyung-Ryong, Chae, Han-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530295/
https://www.ncbi.nlm.nih.gov/pubmed/33010578
http://dx.doi.org/10.1016/j.redox.2020.101727