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The correlation of IRE1α oxidation with Nox4 activation in aging-associated vascular dysfunction
Oxidative stress attributable to the activation of a Nox4-containing NADPH oxidase is involved in aging-associated vascular dysfunction. However, the Nox4-induced signaling mechanism for the vascular alteration in aging remains unclear. In an aged aorta, the expression of Nox4 mRNA and protein by No...
Autores principales: | Lee, Hwa-Young, Kim, Hyun-Kyoung, Hoang, The-Hiep, Yang, Siyoung, Kim, Hyung-Ryong, Chae, Han-Jung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530295/ https://www.ncbi.nlm.nih.gov/pubmed/33010578 http://dx.doi.org/10.1016/j.redox.2020.101727 |
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