Penetrating Ballistic-Like Brain Injury Leads to MicroRNA Dysregulation, BACE1 Upregulation, and Amyloid Precursor Protein Loss in Lesioned Rat Brain Tissues

Severe traumatic brain injury (TBI) is a risk factor for neurodegenerative diseases. Yet, the molecular events involving dysregulated miRNAs that may be associated with protein degradation in the brain remains elusive. Quantitation of more than 800 miRNAs was conducted using rat ipsilateral coronal...

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Detalles Bibliográficos
Autores principales: Thangavelu, Bharani, Wilfred, Bernard S., Johnson, David, Gilsdorf, Janice S., Shear, Deborah A., Boutté, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530327/
https://www.ncbi.nlm.nih.gov/pubmed/33071724
http://dx.doi.org/10.3389/fnins.2020.00915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530327/
https://www.ncbi.nlm.nih.gov/pubmed/33071724
http://dx.doi.org/10.3389/fnins.2020.00915

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