Intratumoral Translocation Positive Heterogeneity in Pediatric Alveolar Rhabdomyosarcoma Tumors Correlates to Patient Survival Prognosis

Alveolar rhabdomyosarcoma (ARMS) is characterized by one of three translocation states: t(2;13) (q35;q14) producing PAX3-FOXO1, t(1;13) (p36;q14) producing PAX7-FOXO1, or translocation-negative. Tumors with t(2;13) are associated with greater disease severity and mortality than t(1;13) positive or t...

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Detalles Bibliográficos
Autores principales: Gleditsch, Katrina, Peñas, Jorge, Mercer, Danielle, Umrigar, Ayesha, Briscoe, James, Stark, Matthew, Tsien, Fern, Hollenbach, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530338/
https://www.ncbi.nlm.nih.gov/pubmed/33072748
http://dx.doi.org/10.3389/fcell.2020.564136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530338/
https://www.ncbi.nlm.nih.gov/pubmed/33072748
http://dx.doi.org/10.3389/fcell.2020.564136

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