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Revisiting the Idea That Amyloid-β Peptide Acts as an Agonist for P2X7
The P2X7 receptor (P2X7) is a cell surface ligand-gated ion channel, activated by its physiological nucleotide agonist ATP and a synthetic analog (BzATP). However, it has also been suggested that there may be structurally unrelated, non-nucleotide agonists such as the amyloidogenic β peptide. Here w...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530339/ https://www.ncbi.nlm.nih.gov/pubmed/33071753 http://dx.doi.org/10.3389/fnmol.2020.00166 |