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IbpB‐bound substrate release in living cells as revealed by unnatural amino acid‐mediated photo‐crosslinking
Small heat shock proteins (sHSPs) are known to bind non‐native substrates and prevent irreversible aggregation in an ATP‐independent manner. However, the dynamic interaction between sHSPs and their substrates in vivo is less studied. Here, by utilizing a genetically incorporated crosslinker, we char...
Autores principales: | Shi, Xiaodong, Ezemaduka, Anastasia N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530376/ https://www.ncbi.nlm.nih.gov/pubmed/32812699 http://dx.doi.org/10.1002/2211-5463.12957 |
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