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Vortioxetine induces apoptosis and autophagy of gastric cancer AGS cells via the PI3K/AKT pathway

Vortioxetine is a potent antagonist of the 5‐hydroxytryptamine receptor and serotonin transporter and has been reported to function as an antidepressant in the treatment of major depressive disorder. However, its antitumor effects remain unclear. Here, we examined whether vortioxetine affects the ch...

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Detalles Bibliográficos
Autores principales: Lv, Gao‐Bo, Wang, Ting‐Ting, Zhu, Hai‐Lin, Wang, Hong‐Ke, Sun, Wen, Zhao, Li‐Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530385/
https://www.ncbi.nlm.nih.gov/pubmed/32750222
http://dx.doi.org/10.1002/2211-5463.12944